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Learn: Blood Clotting and Cardiovascular Disease
Edexcel A Level Biology SNAB A
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Welcome!Building on your knowledge of the heart and blood vessels and cardiac cycle, this lesson will explore blood clotting and its role in cardiovascular disease. Let's dive in!
What is Blood Clotting?Blood clotting is the process by which blood forms a solid plug to stop bleeding from an injury. It involves platelets and proteins like fibrin, which create a mesh to seal wounds.
How Does Blood Clotting Work?When a blood vessel is damaged, platelets stick to the site and release chemicals to start clot formation. A cascade of reactions activates fibrinogen, turning it into fibrin, which forms a mesh to stabilise the clot.
Quick check: Which protein forms the mesh in a blood clot?
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What is Cardiovascular Disease?Cardiovascular disease refers to conditions affecting the heart and blood vessels, such as coronary heart disease. It can result from issues like atherosclerosis (plaque buildup in arteries).
Blood Clots and AtherosclerosisAtherosclerosis can lead to blood clot formation when plaques rupture. This can block blood flow, causing heart attacks or strokes.Clots in coronary arteries reduce oxygen delivery to heart tissue, impairing its function.
During blood clotting, {{blank0}} stick to the damaged site and release chemicals to start the process. This leads to the activation of {{blank1}}, which forms fibrin.
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Risk Factors for Cardiovascular DiseaseKey risk factors include high blood pressure, smoking, high cholesterol, obesity, and lack of exercise. These contribute to plaque buildup and clot formation.
Match the items on the left with their correct pairs on the right
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Review Time!Great work! You've learned about blood clotting, cardiovascular disease, and their connection. Let's test your understanding with a few questions.
Which of the following are stages of blood clotting? (Select all that apply)
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Which condition is caused by plaque buildup in arteries?
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Clots in the {{blank0}} arteries can lead to heart attacks.
Start the lesson to answer this fill in the blank question
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