Combined Science
GCSEOCR

Combined Science

Curriculum Modules

Cells as the basic unit of life
Plant cells vs animal cells: key similarities and differences
Prokaryotic cells vs eukaryotic cells
Cell organelles and their functions
Using a light microscope safely and correctly
Preparing slides and using stains to improve contrast
Calculating magnification and image size
Comparing light and electron micrographs (what each can show)
The role of DNA in cells (genetic material as a code)
Proteins as biological molecules with specific functions
Enzymes as biological catalysts
Lock-and-key model and enzyme specificity
Factors affecting enzyme activity: temperature, pH, substrate concentration
What respiration is and why cells need it
Aerobic respiration: word equation and key ideas
Anaerobic respiration in muscles
Anaerobic respiration in microorganisms (fermentation basics)
Comparing aerobic vs anaerobic respiration (energy release)
Respiration as an enzyme-controlled process
Using respiration ideas to explain exercise and recovery
Interpreting simple data about respiration rate
Photosynthesis as a chemical reaction in plants
The word equation and what it means
Chloroplasts and chlorophyll: where photosynthesis happens
How light intensity affects photosynthesis
How carbon dioxide concentration affects photosynthesis
How temperature affects photosynthesis
Limiting factors and predicting the rate-limiting factor
Using glucose made in photosynthesis (storage and transport)
Linking photosynthesis and respiration in ecosystems
Diffusion: what it is and what affects the rate
Osmosis: movement of water and partially permeable membranes
Active transport: moving substances against a concentration gradient
Comparing diffusion, osmosis and active transport
From cells to tissues to organs to organ systems
Mitosis as cell division for growth and repair
Stem cells: what they are and why they matter
Exchange surfaces: what makes them efficient
Plant transport tissues: xylem and phloem (what they carry)
Transpiration basics and why plants lose water
Surface area to volume ratio and why it matters
Diffusion distance and exchange efficiency
Why multicellular organisms need transport systems
The human circulatory system: overview and purpose
Double circulatory system in mammals
The heart: chambers, valves and blood vessels
Arteries, veins and capillaries: structure and function
Blood components: plasma, red cells, white cells and platelets
Gas exchange in the lungs: structure and function of alveoli
Interpreting circulatory/gas exchange data in exam-style questions
The nervous system: CNS, sensory receptors and effectors
Stimulus–response pathways and survival value
Reflex actions and reflex arcs
Synapses (simple model) and neurotransmitters
The endocrine system and hormone signalling
Comparing nervous vs hormonal control
Homeostasis: maintaining stable internal conditions
Thermoregulation: sweating, shivering and blood flow changes
Blood glucose control: insulin and glucagon
Diabetes (type 1 and type 2 at GCSE level)
Kidneys and osmoregulation (water balance)
Negative feedback as a control mechanism
What an ecosystem is (biotic and abiotic factors)
Levels of organisation: organism to community to ecosystem
Food chains and trophic levels
Food webs and interdependence
Competition and predator–prey relationships
Pyramids of number, biomass and energy
Decomposers and nutrient recycling
The carbon cycle
The water cycle
Biodiversity: what it means and why it matters
Human impacts on ecosystems (habitat loss, pollution)
DNA, genes and chromosomes: the big picture
Genetic terms: genotype, phenotype and alleles
Dominant and recessive inheritance
Monohybrid crosses using Punnett squares
Inherited disorders (using clear examples)
Sex determination (XX/XY) and inheritance patterns
Variation: genetic vs environmental
Mutation as a source of new variation
Natural selection: how it works, step by step
Evolution and adaptation (linking to survival and reproduction)
Selective breeding: process, benefits and drawbacks
Antibiotic resistance as an example of evolution in action
Monitoring ecosystems and environmental change
Pollution and biodiversity: causes and consequences
Food security: why feeding humans is challenging
Increasing food production: farming methods and trade-offs
Fertilisers and eutrophication (cause → effect chains)
Genetic modification in crops: potential benefits and concerns
Health and disease: what the terms mean
Communicable vs non-communicable diseases
Pathogens (virus, bacteria, protist, fungi) and how disease spreads
Plant diseases and human infections (named examples)
Reducing spread: hygiene, isolation, plant control measures
White blood cells and platelets: how they protect the body
Non-specific defences (skin, mucus, stomach acid)
Vaccination: how vaccines work and why they’re used
Antibiotics, antivirals and antiseptics (what each is for)
Developing new medicines: preclinical and clinical testing
Lifestyle factors and disease risk (smoking, diet, exercise, alcohol)
Solids, liquids and gases in the particle model
Explaining density using particles
Explaining diffusion using particles
Gas pressure in terms of particle collisions
Changes of state and heating/cooling curves
Internal energy and temperature (what changes and why)
Atomic structure: protons, neutrons and electrons
Isotopes and relative atomic mass
Electronic structure (simple shell model)
The Periodic Table: periods and groups
Metals vs non-metals: typical physical properties
Using atomic structure to explain simple reactivity patterns
Elements, compounds and mixtures: clear definitions
Pure substances and impurities
Filtration, crystallisation and simple distillation
Fractional distillation (separating liquids)
Paper/TLC chromatography: how separation works
Reading chromatograms and calculating Rf values
Choosing the best separation technique for a substance
Ionic bonding: electron transfer and ion formation
Covalent bonding: sharing electrons and molecules
Metallic bonding: why metals conduct and are malleable
Giant ionic structures vs simple molecular substances
Polymers: repeating units and basic properties
Materials: ceramics, polymers, composites and alloys (uses)
Writing word equations and balancing symbol equations
Conservation of mass (reactants vs products)
Exothermic and endothermic reactions
Reaction profiles (energy changes)
Acids and alkalis: pH and neutralisation
Making salts (including crystallisation of a soluble salt)
Reactivity series of metals (patterns and uses)
Displacement reactions (metal and halogen examples)
Oxidation and reduction (electron/oxygen ideas at GCSE level)
Electrolysis: what it is and why ions matter
Electrolysis of molten ionic compounds (products at electrodes)
Electrolysis of aqueous solutions (how products are chosen)
Using the Periodic Table to predict chemical behaviour
Group 1 metals: reaction patterns (water and oxygen)
Group 7 halogens: reaction patterns and displacement
Noble gases: why they’re unreactive
Naming key compounds from formulas (basic GCSE set)
Identifying ions with flame tests and simple precipitation tests
Identifying gases (hydrogen, oxygen, carbon dioxide, chlorine)
Using tests to identify unknown substances in exam questions
Using observations to infer reaction type
Collision theory: why reactions happen at different speeds
Measuring rate: gas volume, mass change, precipitation
Factors affecting rate: temperature, concentration, surface area
Catalysts and enzymes (comparing role as catalysts)
Interpreting rate graphs (tangent/gradient ideas)
Reversible reactions and dynamic equilibrium
Le Chatelier’s principle (temperature, pressure, concentration)
Equilibrium in industrial processes (Haber process context)
Yield, atom economy and sustainability links
Finite resources and sustainable chemistry choices
Life-cycle assessments: what they include and why they matter
Recycling: benefits, limitations and real-world trade-offs
Crude oil as a resource and why it’s useful
Fractional distillation of crude oil: fractions and uses
Cracking hydrocarbons: conditions and products
Alkanes and the homologous series (patterns in formulas)
Polymer production and environmental impacts
Earth’s atmosphere: changes over time (GCSE narrative)
Greenhouse effect vs climate change (separating ideas clearly)
Human activity and atmospheric composition (evidence-based links)
Potable water production and wastewater treatment (core stages)
Particle model in physics (motion and spacing)
Density: measuring, calculating, and interpreting results
Pressure in fluids (qualitative + simple calculations)
Moments and turning effect in everyday contexts (if assessed in suite questions)
Changes of state: melting, boiling, evaporation, condensation
Latent heat and why temperature stays constant during change of state
Heating curves: reading and sketching from data
Gas pressure and temperature/volume trends (basic model)
Distance, time and speed: core definitions
Using distance–time graphs
Velocity and acceleration (what they mean)
Using velocity–time graphs (including distance from area)
Calculating acceleration from data/graphs
Newton’s first law: inertia and balanced forces
Newton’s second law: force, mass and acceleration
Newton’s third law: action–reaction pairs
Weight, mass and gravitational field strength
Friction, drag and terminal velocity
Stopping distance: thinking and braking distance factors
Hooke’s law and spring extension
Work done by a force and energy transfer in motion
Static charge: build-up, attraction and discharge
Current as rate of flow of charge
Potential difference and what it represents
Series circuits: current, potential difference and resistance rules
Parallel circuits: current splitting and shared potential difference
Resistance and the I = V/R relationship
Measuring current and potential difference correctly
I–V characteristics for ohmic conductors and non-ohmic components
Power in electrical devices (power, energy and time links)
Mains electricity safety: live, neutral, earth, fuses
Magnets and magnetic fields (field lines and poles)
Electromagnets: making and strengthening them
Using electromagnets in real devices (relays, motors context)
Transverse vs longitudinal waves
Describing waves: amplitude, wavelength, frequency, period
The wave equation and basic calculations
Reflection and refraction (ray ideas and wave speed changes)
Sound waves: pitch, volume and oscilloscopes (core interpretation)
Electromagnetic spectrum: order and key uses
Hazards and safety with different EM waves
Radioactivity: what it is and why nuclei are unstable
Alpha, beta and gamma: properties and penetration
Irradiation vs contamination
Half-life (interpreting graphs and simple calculations)
Background radiation and risk
Energy stores and pathways (transfers)
Conservation of energy and Sankey diagrams
Work done as energy transferred
Kinetic and gravitational potential energy calculations
Elastic potential energy in springs (GCSE calculation focus)
Power: what it means and how to calculate it
Efficiency and why no process is 100% efficient
Ways to improve efficiency in everyday systems
Energy resources: comparing reliability and environmental impact
Physics on the move: forces and energy in transport
Reducing unwanted energy transfers in vehicles
Braking and safety features explained with forces/energy ideas
Powering Earth: how electricity is generated
Non-renewable vs renewable resources: pros and cons
National and local issues: demand, reliability and cost
Transformers (core idea: stepping voltage up/down)
Transmission efficiency and why high voltage is used
Storing energy from renewables (batteries, pumped storage context)
Lab safety: hazards, risks and control measures
Writing a clear method that can be repeated
Identifying independent, dependent and control variables
Accuracy, precision, repeatability and reproducibility
Estimating uncertainty and spotting anomalous results
Recording data in suitable tables (headings, units, resolution)
Drawing graphs correctly (scales, labels, best-fit lines)
Interpreting gradients and areas where relevant
Sampling techniques and using means appropriately
Required apparatus and techniques
Planning and evaluating practical investigations (improvements and limitations)
Linking practical methods to exam questions (methods, variables, calculations, conclusions)
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